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ADC Therapeutics stock halves after Zynlonta Phase III records three times more deaths than control arm

The Lausanne-based company said its Phase III LOTIS-5 trial met its primary endpoint, showing that Zynlonta (loncastuximab tesirine) plus rituximab, the anti-CD20 antibody that remains a backbone of B-cell lymphoma treatment across multiple lines of therapy, significantly improved progression-free survival compared with rituximab plus a chemotherapy regimen consisting of gemcitabine and oxaliplatin, commonly known as R-GemOx, in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The study enrolled 440 patients after at least one prior line of systemic therapy.

Twin Prime Editing Enables Rapid Trait Stacking in Crops

Researchers working to advance genome engineering in crops face many challenges, including simultaneously introducing diverse genome edits. Although a major goal of modern crop breeding is to efficiently combine multiple desirable traits by “stacking” the favorable alleles that contribute to those traits in a single crop variety, current strategies are time-consuming and inefficient.

Krone into pickup rake technology

While rotary rakes are particularly effective for grass and straw from stemmed crops such as cereals, pickup rakes offer clear advantages for leafy and herbaceous crops such as lucerne or clover. Thanks to the Swativo T 1040 Pro’s gentle collection and conveyance of the crops, leaf loss is minimised and forage quality is further improved.

Lilly and Boehringer pause $2bn German investments over planned drug-spending curbs

Lilly announced that it would reduce the not-yet-implemented part of its major project in Alzey, in the Rhineland-Palatinate region, by around half. The production facility for biopharmaceutical medicines is still scheduled to begin operations in 2027, but with lower capacity than originally planned. According to the company, investments of up to US$1.5bn, as well as a significant share of the jobs originally planned, are now in question.

What investors should know before backing AI tools for food waste management: report

AI tools for measuring and managing food waste are gaining traction, but adoption remains fragmented, with companies rel…

Bio-Techne, Refeyn Partner on Workflow for Bispecific Antibody, Biosimilar Characterization

This week, Bio-Techne, a provider of life science tools, reagents, and diagnostic product, and Refeyn, a pioneer in mass photometry technology, announced the launch of an integrated workflow for characterizing charge and size variants in bispecific antibodies and biosimilars. 

5 GAI Australia Sessions You Won’t Want to Miss

By Autumn Demberger, AgInvesting MediaNext week, the global agriculture investment sector will join together in the heart of Brisbane, Australia for the inaugural GAI Australia summit, taking place June 10-11. For the first time in its near-two-decade history, Global AgInvesting (GAI)—the world’s premier gathering for agriculture, water, timberland, and natural capital stakeholders—is heading to the Southern Hemisphere.

More spraying capacity

Designed for large scale farming, the MY27 500R series builds on the existing front-cab, rear-engine concept and enters a higher productivity segment while maintaining a compact transport width of just 2.55 m. Headline addition is the new 560R model, expanding the 500R range into the 6,000-liter class. The larger tank is aimed at operators working tight application windows who need to cover more hectares per day with fewer refilling stops, particularly in cereals, oilseed rape and other high-input crops. The 560R complements the existing 4,000- and 5,000-liter models, providing a broader choice within a single platform.

GERBER-RAUTH exits dairy commodities to double down on ‘future of dairy’

Milan-based private investment company GERBER-RAUTH has sold dairy commodities broker and trader L’Interform to Atlante,…

ESG: Proving Queensland’s Credentials

By the Queensland GovernmentResponsible investors looking to manage ESG risk will find strong alignment with Queensland’s primary industries sector, known globally for its reputation in producing high-quality, safe and sustainable produce that meets strict production, processing, transport and animal welfare standards