In Massachusetts, Latest Annual Snapshot Shows a Tale of Two Biopharmas
Massachusetts, the home of the nation’s leading biopharma cluster as ranked by GEN, offers a study in contrasts when it comes to the health of the sector, as revealed by an industry group.
Expanded Synthetic Promoter Library Introduced to Boost Biomanufacturing Operations
SynGenSys, based in Sheffield, U.K., reports that it has introduced its CHO.SET® 2.0 synthetic gene promoter system to improve protein production in CHO (Chinese Hamster Ovary) cells.
Neural Mechanism Identified That Drives Increased Alcohol Use in Isolated Male Mice
A preclinical study led by researchers at Northwestern University and the Salk Institute for Biological Studies has found that loneliness can reprogram the brain in ways that push alcohol consumption, in males.
Pioneering Study of Alpha-Gal Syndrome Launched at Martha’s Vineyard Hospital
Alpha-gal syndrome (AGS)—also known as red meat allergy—is an allergy transmitted through ticks. Alpha-gal (galactose-α-1,3-galactose) is naturally produced in the bodies of most mammals, but not people. It is also found in the saliva of some ticks and is transferred in a tick bite into a person’s blood, leading to an allergic reaction. Symptoms, which can include hives, gastrointestinal distress, breathing difficulties and, in severe cases, anaphylaxis, occur after people eat red meat or are exposed to other products made from mammals. Unlike many food allergies, reactions often occur several hours after eating, which can make diagnosis difficult.
PARP Inhibitor Combination Therapy Boosts Antitumor Activity in NSCLC Models
Drug resistance remains a central obstacle in the treatment of non-small cell lung cancer (NSCLC) and other lung cancers, even as targeted therapies have improved outcomes for patients whose tumors are driven by mutations in EGFR, KRAS, or other oncogenes. Now, a preclinical study suggests that pairing the HER3-targeting antibody-drug conjugate HER3-DXd with the PARP inhibitor olaparib could offer a way to intensify DNA damage in tumor cells while also stimulating antitumor immune activity.
Male Sex Hormones Suppress Lung Allergies by Acting on Neurons in Mice
Sex-related differences in the rates of asthma onset and remission suggest that sex hormones may play a role in the pathogenic mechanisms that underly some forms of asthma. A study led by researchers at Peking University Third Hospital Cancer Center, Peking University, has now found that in mice, male sex hormones can suppress allergic responses by promoting sympathetic nerve connections and norepinephrine release in the lungs. The findings help to illuminate mechanisms that underlie sex differences in allergic diseases and could help inform future therapeutics to treat type 2 immune inflammatory conditions such as asthma.
Rznomics Joins Lilly Gateway Labs to Quicken RNA Therapeutic Candidate Discovery and Development
Rznomics is joining Lilly Gateway Labs (LGL) in San Diego. The company is a clinical-stage biopharmaceutical firm based in South Korea focused on developing RNA-based gene therapies.
Regent to acquire Avon North America, reuniting it with international arm
Regent will acquire the entirety of LG Household & Health Care’s (LG H&H) stake in Avon North America. Avon International and North America will be reunited under the global investment firm.
FAO Director-General: Unlocking Horticulture’s Potential Is Key To Transforming Agrifood Systems And Delivering Healthy Diets For All
August 2026, Rome: Agriculture must move beyond a primary focus on producing sufficient quantities of food and place gre…
GAI West Connect
The GAI West Coast Connect is built for a different purpose: direct, curated connection between institutional investors, family offices, endowments, foundations, and the fund managers and operators who work alongside them.
