Swiss VC Redalpine closes eighth fund at $250 million
Its predecessor, Redalpine Capital VII, closed at $200 million in 2024. The new fund is therefore 25% larger. This development contrasts with the overall decline in fundraising in German-speaking countries. According to PitchBook data, 83 venture capital funds closed in 2022, raising a combined €6.2 billion. In the first nine months of 2025, only 21 funds closed, raising a total of €2 billion. The median time between a fund’s launch and final closing most recently stood at 26 months.
Boehringer-Zealand obesity drug clears cardiovascular safety hurdle, but tolerability concerns remain
Why it matters: According to Zealand Pharma, the November 9 SYNCHRONIZE-CVOT results complete the registrational Phase 3 program intended to support Boehringer’s planned regulatory submissions for obesity. Boehringer describes it as “the first and only global cardiovascular safety trial of a glucagon/GLP-1 dual agonist to date.”
Oyster Therapeutics raises $60M to bring Alzheimer’s tau degrader to clinic
Why it matters: Approved disease-modifying treatments for Alzheimer’s, including Leqembi and Kisunla, target amyloid plaques in the brain. Oyster is pursuing another hallmark of the disease: abnormal accumulations of tau inside neurons, which are associated with neuronal damage and cognitive decline.
Novo, Novartis drugs cut heart-risk markers but not cardiovascular events
Why it matters: Both trials tested ways to prevent heart attacks and strokes beyond lowering LDL cholesterol, one by suppressing inflammation and the other by reducing lipoprotein(a) (Lp(a)) a largely inherited cardiovascular risk factor elevated in approximately one in five people. Their failures challenge two closely watched drug-development strategies but do not establish conclusively that either biological target is ineffective.
Windward targets $204M IPO; Valneva’s Shigella vaccine meets Phase 2 endpoint; Ethris’ nasal mRNA lowers viral load
Windward targets $204 million from IPO and Sanofi placement: The Swiss biotech plans to offer approximately 10.3 million shares at $16–$18 each. At the midpoint, the offering and a separate $50 million Sanofi investment would generate approximately $203.8 million in combined net proceeds. Founded in 2024 and publicly launched in January 2025 with a $200 million Series A, Windward is pursuing Nasdaq less than two years after launch, following its $165 million Series B. Its model combines experienced leadership — CEO Luca Santarelli previously built Therachon and VectivBio — with clinical-stage medicines licensed from China. The proceeds would support respiratory and dermatology studies of WIN378, an anti-TSLP antibody, and WIN027, which targets TSLP and IL-13. The IPO remains pending.
Neobe raises $6.8M to break tumor barriers with bacteria
Why it matters: Immunotherapies such as checkpoint inhibitors have transformed cancer treatment, but many patients do not respond. One reason is the tumor microenvironment: a dense network of proteins and other molecules surrounding cancer cells that can prevent immune cells from reaching their targets.
Immunocore doubles up on T-cell engagers in eye cancer
Why it matters: The early result exceeds the 45% two-year survival seen with Kimmtrak alone in its landmark Phase 3 trial, raising the possibility that attacking two tumor targets could improve on the existing treatment for this rare and aggressive eye cancer.
Arcus Compliance launches SaaS assistant to track beauty regulations
Regulatory consultancy Arcus Compliance has launched a SaaS (software as a service) tool to streamline monitoring and adherence to UK and European regulatory requirements. Mavryx Assistant is designed to support founders, start-ups, and brands in the beauty industry.
Estée Lauder anchors portfolio-wide innovation in skin longevity science
The Estée Lauder Companies (ELC) has debuted a longevity-focused scientific innovation platform, Mastering Skin Longevity. The platform is touted to advance the beauty giant’s ingredient innovations, technologies, formulations, and future product development.
Allergan Aesthetics studies target “Ozempic face” with injectable treatments
Allergan Aesthetics has found that weight-loss drug patients who use injectable aesthetic treatments experience increased satisfaction with their facial appearance, according to two Phase 4 studies. The studies, Harmony in Diversity and Halo, examined how injectables might address skin care concerns associated with GLP-1 use.
