月度归档： 2026 年 8 月

Alpha-gal syndrome (AGS)—also known as red meat allergy—is an allergy transmitted through ticks. Alpha-gal (galactose-α-1,3-galactose) is naturally produced in the bodies of most mammals, but not people. It is also found in the saliva of some ticks and is transferred in a tick bite into a person’s blood, leading to an allergic reaction. Symptoms, which can include hives, gastrointestinal distress, breathing difficulties and, in severe cases, anaphylaxis, occur after people eat red meat or are exposed to other products made from mammals. Unlike many food allergies, reactions often occur several hours after eating, which can make diagnosis difficult.

Drug resistance remains a central obstacle in the treatment of non-small cell lung cancer (NSCLC) and other lung cancers, even as targeted therapies have improved outcomes for patients whose tumors are driven by mutations in EGFR, KRAS, or other oncogenes. Now, a preclinical study suggests that pairing the HER3-targeting antibody-drug conjugate HER3-DXd with the PARP inhibitor olaparib could offer a way to intensify DNA damage in tumor cells while also stimulating antitumor immune activity.

Sex-related differences in the rates of asthma onset and remission suggest that sex hormones may play a role in the pathogenic mechanisms that underly some forms of asthma. A study led by researchers at Peking University Third Hospital Cancer Center, Peking University, has now found that in mice, male sex hormones can suppress allergic responses by promoting sympathetic nerve connections and norepinephrine release in the lungs. The findings help to illuminate mechanisms that underlie sex differences in allergic diseases and could help inform future therapeutics to treat type 2 immune inflammatory conditions such as asthma.

Rznomics is joining Lilly Gateway Labs (LGL) in San Diego. The company is a clinical-stage biopharmaceutical firm based in South Korea focused on developing RNA-based gene therapies.