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New Zika Virus Vaccine Approach Harnesses the Power of T Cells in Mice
Zika virus is easy to underestimate. For many people, infection causes no symptoms at all, or only a fever, rash, and joint pain. But when the mosquito-borne virus spread explosively through the Americas in 2015 and 2016, it exposed a far darker side: infection during pregnancy could impact fetal brain development, causing microcephaly and other birth defects now grouped as congenital Zika syndrome.
Apollo vaccine triggers broad rhinovirus immunity in Phase 1
Why it matters: Rhinovirus is a major trigger of chronic obstructive pulmonary disease (COPD) exacerbations, but its roughly 180 strains have frustrated attempts to develop a broadly protective vaccine. There are currently no approved vaccines or targeted treatments for the virus.
Immatics adds $150M ahead of anzu-cel readout
Why it matters: Anzu-cel is approaching its decisive clinical and regulatory milestones and Immatics is simultaneously expanding its Phase 3 programme and preparing for a potential commercial launch.
跨越实验室与产线鸿沟：美国CJB Applied Technologies携粉末混合与颗粒包衣放大方案亮相FAT2026
世界农化网中文网报道：在农化制剂从实验室研发迈向规模化生产的过程中，工艺放大始终是研发人员最头疼的″拦路虎″。很多配方在实验室里表现优异，可一上大生产设备，就暴露出混合不均、包衣脱落、批次间质量波动大等问题——研发进度被一再拖后，试错成本水涨船高，甚至可能错失最佳的市场窗口。更现实的问题是：如何在研发早期，用尽可能低的成本，提前预判并解决放大生产中的潜在风险？