Danish biosolutions group Novonesis has signed an agreement with Singapore-based TurtleTree to scale, manufacture and commercialize the latter’s precision-fermented lactoferrin ingredient, LF+®. Novonesis is also making a minor investment in TurtleTree, joined by 321Catalyst Ventures, the corporate venture arm of Mitsui Chemicals.
Under the deal, Novonesis will exclusively handle scaling, manufacturing and commercialization of LF+® for the early life nutrition market, with selected commercial rights extending to dietary supplements. Copenhagen-headquartered Novonesis was formed in January 2024 through the merger of Novozymes and Chr. Hansen and describes the agreement as complementary to its existing Human Health Biosolutions portfolio, which includes human milk oligosaccharides, probiotics and synbiotics.
Addressing a supply-constrained ingredient
Lactoferrin is an iron-binding protein found in milk, valued for its role in immunity, iron regulation and gut health, particularly for women and infants. Conventional extraction requires large volumes of milk, which according to the companies limits supply and drives up cost. TurtleTree, founded in 2019 by Fengru Lin and Max Rye, produces LF+® through precision fermentation and became the first company globally to receive a “No Objection Letter” from the US FDA under GRAS for a precision-fermented lactoferrin. The ingredient also secured vegan certification from Vegan Action and has since been used in commercial launches with Cadence Performance Coffee and Strive Nutrition.
Image courtesy of TurtleTree
Thomas Batchelor, Senior Vice President for Early Life and Specialized Nutrition at Novonesis, said, “Our aim is to make lactoferrin more accessible and cost-competitive and showcase what is achievable with precision fermentation in early life nutrition and dietary supplements. If successfully scaled, this will enable customers to deliver proven health benefits to consumers more efficiently. LF+® fits well in our broader portfolio of both precision fermentation projects and our specialized nutrition ingredients.”
Manufacturing capacity paired with a fermentation platform
The arrangement pairs TurtleTree’s fermentation technology with Novonesis’s existing manufacturing and commercial infrastructure, an approach the companies frame as addressing cost and supply consistency at scale rather than technical feasibility alone.
Fengru Lin, Founder and CEO of TurtleTree, said: “This partnership is about doing the hard work required to make the unique benefits of lactoferrin truly usable at scale. Not just technically, but economically available for all.
“By pairing TurtleTree’s precision fermentation platform with Novonesis’ manufacturing and commercialization capabilities, we’re unlocking the consistency, cost structure, and supply reliability that modern health brands need. Ultimately, this enables our customers to formulate with confidence and deliver meaningful benefits to the people who rely on these products every day.”
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